The M-10 federal highway partially lies through the Novgorod region.
It begins in Moscow and runs through Tver, Veliky Novgorod, St. Petersburg.
It ends at the international border with Finland.
M-10 Legend is description of all the villages and cities on the highway, information on gas stations, car service and restaurants. In Russian only (source).
There is also M-11 - a high-speed highway between Moscow and St. Petersburg, one of the first large toll roads in Russia. The total length of the road is 669 km. The route starts from Moscow and passes through the Moscow, Tver, Novgorod and Leningrad regions to St. Petersburg.
Rest areas of M-11